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This powerful cascade of events can happen in a matter of seconds, and bring it back to the lab.
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The invention relates to a process for the preparation of pharmaceutical preparations based on cis-platinum II -diamine dichloride using an aqueous-alcoholic carrier. The process of the invention allows the preparation of sterile and stable freeze-dried forms of cis-platinum II diamine dichloride containing mg of active ingredient, which forms can be prepared on an industrial scale and dissolved readily and rapidly, is used in a more advantageous and rational way in anti-tu-mother chemotherapy in comparison with the frozen forms of cis-platinum II -diamine chloride currently marketed.
These properties are obtained as a result of special precautions in the composition concentration of the solution to be freeze-dried, introduction of alcohols, adjustment of the pH of the solution to an appropriate value and as a result of the use of a preparation technique which as a final step includes freeze-drying of cis-platinum II diamine dichloride in aqueous-alcoholic medium.
The method of preparation, and especially the freeze-drying process, has been found to be economically advantageous and has enabled the very significant problems associated with freezing-drying cis-platinum II -diamine chloride in aqueous medium breakage of containers, very low yields to be solved. The inorganic platinum complexes constitute a very large class of substances possessing anti-tumor activity.
The antibiotic effect of such complexes was first discovered in by Rosenberg et al. Rosenberg et al. Attention was focused on the ability of these compounds to block the proliferation of certain test tumors in laboratory animals.
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Log in to get trip updates and message other travelers. Klebaek Hoje 3 Reviews. Historic Sites. Sorry, there are no tours or activities available to book online for the date s you selected. Please choose a different date.
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Weeks after Ben Affleck and Knives Out actress Ana de Armas wrapped their next movie together, the costars were seen having dinner in her native Cuba. The actors were spotted while out to eat and walking around Havana on Thursday, where de Armas is from. The two were pictured smiling and laughing on a walk around the Cuban capital by photographers and fans, who asked to take photos with the stars.
In one group picture , de Armas, 31, stands in front of Affleck, 47, as they smile while surrounded by fans. Another shot from a different outing, this time at restaurant La Corte del Principe, seems to show the two with a cook. The sightings come after the pair wrapped filming on Deep Water , a sexual thriller from Fatal Attraction director Adrian Lyne they shot on location in New Orleans over the winter. Affleck and de Armas had been seen filming throughout the Louisiana city several times, including a day out on a field in November.
The film is set to be released November It seems the two also spent some time together off set while filming as a fan in New Orleans tweeted about spotting them at a bar together in January. Affleck is fluent in Spanish and recently conducted several interviews for his new movie The Way Back in the language. Affleck revealed he picked Spanish up as a second language while filming a series in Mexico in his teens. FB Tweet ellipsis More. Get push notifications with news, features and more.
List of the oldest living people
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Nikolina Brnjac, President-in-Office of the Council. As you know, the December European Council gave us guidance to this effect. We believe that priority should be given to the implementation of the strategic agenda for , agreed in June last year, and to delivering concrete results for the benefit of our citizens. The priorities outlined in the strategic agenda closely echo those raised by our citizens, for instance in the citizen consultations and dialogues. The Conference should build on the success of these dialogues over the last two years.
Yesterday, my Prime Minister underlined how the Conference could be an opportunity to listen to citizens so that we are better able to meet their expectations. We think the Conference should contribute to the development of our policies in the medium and long term so that we can better tackle current and future challenges. We also believe the upcoming Conference should be an inclusive process, involving our three institutions in full respect of the interinstitutional balance of our respective roles.
Likewise, Member States should equally be involved, including their parliaments. Shared ownership is important. The European Council asked the Croatian Presidency to work towards defining a Council position on the content, scope, composition and functioning of a Conference on the Future of Europe and to engage on this basis with the European Parliament and the Commission.
Ben Affleck and Ana de Armas Spotted in Her Native Cuba After Wrapping Thriller Together
This is a list of the 50 oldest people who have been verified to be alive as of the dates of the cited supporting sources. It is estimated that there are between and living people who have reached the age of Kane Tanaka of Japan is the world’s oldest living person whose age has been verified. From Wikipedia, the free encyclopedia. Wikimedia list article. This incomplete list is frequently updated to include new information.
This is a list of the 50 oldest people who have been verified to be alive as of the dates of the Demontier Tenório (5 May ). “Mulher mais idosa do Ceará completa anos hoje em Juazeiro do Norte”. (in Portuguese).
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